Medical Device Quality, Regulatory and Product Development Blog | Greenlight Guru

Most popular medical device content in 2025

Written by Matt McFarlane | December 17, 2025

 

2025 was an eventful year in the medtech landscape, with plenty of changes happening within the industry.

Something that hasn’t changed, however, is our commitment to bringing you timely, informative, and high-quality content on all the latest updates in medtech. Whether you prefer to read, watch, or listen, we’ve got you covered. We looked through our entire content output for the year, found our most popular blogs, webinars, and podcasts, and brought them together in one place.

There’s something here for everyone, so see what grabs your interest and enjoy!

BONUS RESOURCES: Click here to download a free QMSR readiness playbook filled with resources to help you prepare for February 2026.

Top 10 Medical Device Blog Posts

The Greenlight Guru Medical Device Blog provides actionable tips, best practices and insights for better medical device quality, compliance and product development. Join 200,000+ other MedTech professionals outperforming their peers by subscribing to our newsletter.

How to create a quality manual per ISO 13485 (plus free template)

This post explains how to create a Quality Manual that meets the ISO 13485:2016 standard, emphasizing that the manual serves as the essential navigational table of contents for a company's Quality Management System (QMS).

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11 questions to ask QMS software vendors in the medical device industry

This article provides 11 essential questions medical device companies should ask QMS software vendors to ensure the solution meets industry-specific needs. The questions focus on regulatory alignment, built-in compliance workflows, and closed-loop traceability.

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How to build your own GSPR checklist (plus free template)

This post guides medical device companies on how to conform with the General Safety and Performance Requirements (GSPR) of the EU MDR, which is mandatory for placing a device on the EU market. It recommends using a GSPR checklist to demonstrate compliance by referencing applicable harmonized standards.

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Top 50 venture capital firms for medical device startups

This resource lists the top 50 Venture Capital firms that actively invest in medical device and life sciences startups. It serves as a guide for young MedTech companies seeking crucial financial backing for product development and market launch.

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How to use an FMEA template as part of your medical device risk management

This post explains how to use a Failure Mode Effects Analysis (FMEA) template as a complement to the broader risk management system required by ISO 14971:2019.

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FDA guidances on AI-enabled devices: where AI stands in 2025

This post reviews the FDA's guidance documents on Artificial Intelligence-Enabled Device Software Functions (AI-DSF), focusing on lifecycle management recommendations and the final rule on Predetermined Change Control Plans (PCCP).

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3 key steps for supplier risk assessment in medtech

This article details the three key steps for conducting a risk-based supplier assessment in MedTech to ensure a reliable supply chain and regulatory compliance. The steps involve classifying suppliers by risk level and structuring monitoring activities, like audits, according to that risk.

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3 insights on medtech product development from an Ex-FDA investigator

A former FDA investigator offers three key insights for MedTech product development, advising companies to build a strong foundation of regulatory knowledge and align R&D with production for compliant data collection. 

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What’s left of the QSR in QMSR? Your guide to the new Part 820

This guide explains the new Quality Management System Regulation (QMSR), which harmonizes U.S. FDA 21 CFR Part 820 by incorporating ISO 13485:2016 by reference. It details the few sections of the new Part 820 that retain explicit FDA requirements not fully addressed by the ISO standard.

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Dynamic risk management for software-enabled medical devices

This post advocates for a "Dynamic Risk Management" approach for software-enabled medical devices, contrasting it with static, spreadsheet-based methods. 

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BONUS RESOURCES: Click here to download a free QMSR readiness playbook filled with resources to help you prepare for February 2026..

Top 10 Webinars

Our free training webinars help medical device professionals keep up with industry best practices, navigate regulatory changes, and stay compliant. Here are our most watched webinars of 2025:

FDA disruption: mitigating risk in an unstable U.S. regulatory environment

This webinar discusses the FDA's transition from the Quality System Regulation (QSR) to the Quality Management System Regulation (QMSR), aligning more closely with ISO 13485 standards. You'll learn how to adjust your systems to meet these new regulatory demands.

Access the free on-demand webinar →

Lessons learned: avoiding common mistakes in ISO 13485 certification

This session provides expert perspectives on Post-Market Clinical Follow-up (PMCF) requirements under the EU MDR 2017/745. You'll gain practical guidance on implementing PMCF activities to maintain compliance and ensure device safety.

Access the free on-demand webinar here →

Countdown to QMSR: What you need to know to be ready for February 2026

This webinar offers strategies for transitioning to the FDA's new QMSR framework. Learn the key distinctions between QMSR and ISO 13485 and receive actionable steps to prepare your organization for compliance.


Access the free on-demand webinar →

After QMSR: what FDA investigators will look for, and how to prepare your post-market team now

This session clarifies the FDA's final guidance on medical device cybersecurity, emphasizing risk management throughout the product lifecycle and offering guidance on submission expectations and cybersecurity.

Access the free on-demand webinar →

Navigating AI in medical devices & healthcare – from hype to harmonization

Here, we explore integrating ISO 14971 risk management principles within the new QMSR framework. You'll discover best practices for designing risk processes that meet regulatory expectations and avoid common pitfalls.


Access the free on-demand webinar →

Use related risk analysis & how it applies to medical device development

This session provides updates on global Unique Device Identification (UDI) regulations, focusing on EUDAMED amendments and trends from various health authorities. Viewers will gain valuable insights into developing a practical UDI strategy for product data submissions.

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Device descriptions: the most poorly 
written part of medical device submissions

This webinar examines the FDA's eSTAR 5.0 platform, highlighting changes to cybersecurity, biocompatibility, and clinical data requirements. You'll receive guidance on navigating the platform for successful 510(k), De Novo, or PMA submissions.

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Manufacturing of medical devices, design transfer and heading into the unknown

In this webinar, we delve into IEC 62366-1, focusing on enhancing user safety and device usability, as well as explaining how to implement the standard effectively to improve medical device design and reduce use errors.


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Key regulatory insights for US and EU market access

This webinar addresses the critical phase of transferring medical device design to manufacturing. You'll explore best practices for ensuring a smooth transition, proper documentation, and alignment between design specifications and production needs.

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Mastering the design history file: what to include, why it matters, and how to avoid mistakes

This interactive session featured FDA representatives discussing the final guidance on medical device cybersecurity. Check out what questions your industry peers had around complying with the final guidance on cybersecurity in MedTech.

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BONUS RESOURCES: Click here to download a free content bundle with our top eBooks, tools, and on-demand webinars from 2024.

Top 5 Global Medical Device Podcast Episodes

The Global Medical Device Podcast is where today's brightest minds in the medical device industry go to get their most useful and actionable insider knowledge, direct from some of the world's leading medical device experts and companies.

How To Approach Culture Differences 

Host Etienne Nichols and MedTech founder Olga Chashchina explore how understanding cultural contexts, such as high- versus low-context communication, is essential for successfully managing global teams and improving patient care.

Listen to the full episode →

MedTech 101: What You Need to Know About the Medical Device Industry

Host Etienne Nichols leads a foundational discussion with Sara Adams and Chris Rush, demystifying the MedTech industry by covering medical device definition, FDA classification, regulatory pathways, and design controls.

Listen to the full episode here →

The State of the Medical Device Industry

Host Etienne Nichols and Greenlight Guru's Sara Adams review key findings from the 2025 Medical Device Industry Report, providing a strategic outlook on market growth, supply chain complexity, and regulatory changes like the QMSR.

Listen to the full episode here →

Mastering MedTech Influence: The Power of Communication in Quality

Host Etienne Nichols and executive coach Lesley Worthington discuss the importance of communication in quality, explaining that true influence comes from making others feel understood, not just being technically correct.

Listen to the full episode here →

How to Build a QMS That Actually Works: From Startup to Scale in MedTech

Host Etienne Nichols is joined by Ashkon Rasooli, who outlines a phased approach to QMS implementation, advising companies to build their system proactively in alignment with product development rather than waiting for regulatory checkpoints.

Listen to the full episode here →

BONUS RESOURCES: Click here to download a free content bundle with our top eBooks, tools, and on-demand webinars from 2024.